• Adhesive interactions Adhesive interactions between myeloma

  2019-06-10

  

  Adhesive interactions: Adhesive interactions between myeloma gpr119 agonist and stromal cells play a significant role in both the homing of MM cells to the bone marrow and augmentation of the bone destructive process. These adhesive interactions result in activation of NF-κB and p38 MAP-kinase sign

• igf 1 antagonist br Uganda is on the verge of eliminating th

  2019-06-06

  

  Uganda is on the verge of eliminating the () form of human African trypanosomiasis (HAT), commonly known as sleeping sickness. This elimination would be historic. In 2015, only four cases of this neglected tropical disease were diagnosed in the entire country. A similarly low number of cases in 2

• diacylglycerol kinase Sultan et al retrospectively searched

  2019-06-06

  

  Sultan et al retrospectively searched the surveillance, epidemiology, and end results (SEER) database for patients who were diagnosed with NPC from 1988 to 2006. They compared the clinical features and outcomes of 129 children and adolescents (n and young adults compared with older adults with nasop

• br Conclusion br Conflict of interest br Introduction

  2019-06-06

  

  Conclusion Conflict of interest Introduction Future challenges and conclusion In recent decades several anticancer drugs have been approved for the management and treatment of colorectal cancer. These drugs do not represent a revolution in the treatment of CRC. However, 5-FU has continue

• br The follow up clinic These trial

  2019-06-06

  

  The follow-up clinic These trial results have significant implications for clinic efficiencies. The safe and effective replacement of the bulk of “routine” in-clinic evaluations demonstrated in TRUST (Fig. 3) has a huge implication for resource utilization. Although demanding adjustment to differ

• Introduction Schwannoma is a benign

  2019-06-06

  

  Introduction Schwannoma is a benign tumor of neuroectodermal derivation that originates from Schwann MG 149 which cover the peripheral nerves [3]. Approximately 25–40% of all schwannomas occur in the head and neck. These tumors most commonly arise in the soft tissues of the head and neck and on t

• Introduction Dilated phase hypertrophic cardiomyopathy DHCM

  2019-06-06

  

  Introduction Dilated-phase hypertrophic cardiomyopathy (DHCM) is a rare subset of hypertrophic cardiomyopathy (HCM) [1]. Data available on sustained monomorphic ventricular tachycardia (SMVT) associated with DHCM is scarce. We report a rare case of SMVT caused by a large epicardial scar related to

• br Al comienzo de Elizabeth Corral afirma que la

  2019-06-06

  

  Al comienzo de , Elizabeth Corral afirma que “la escritura de Sergio Pitol tiene una relación orgánica con otras artes” (11). El resto del libro es la comprobación de esta tesis, un recorrido abiertamente personal en el que destacan el ingenio de la mirada y la lucidez para desmenuzar cada uno de

• br En las p ginas de La esquina

  2019-06-06

  

  En las páginas de La esquina de los ojos rojos, jóvenes “pránganas” escapando Lenalidomide toda velocidad sobre una motoneta, una vez cometido un asesinato, huyen a toda costa de una realidad vengativa, de los límites de un vacío personal, ético y de las cerradas posibilidades de esa asfixiante tr

• Tricot muestra las entra as del

  2019-06-06

  

  Tricot muestra las entrañas del Movimiento Mapuche Autonomista con la intención de conducir al lector en la comprensión de la resistencia actual de autoafirmación “ora como pueblo-nación, ora como Identidad Territorial específica”; afirma que el movimiento mapuche “no es un proceso lineal, sino más

• Implementation of contemporary treatment protocols incorpora

  2019-06-05

  

  Implementation of contemporary treatment protocols, incorporating adjuvant chemotherapy, have resulted in an improvement in the prognosis of patients diagnosed with osteosarcoma over the past decades. The overall 5-year survival rate has improved from less than 20% in the 1960s to approximately 60%

• Early repolarization ER is characterized by

  2019-06-05

  

  Early repolarization (ER) is characterized by elevation of the QRS-ST junction (J point) and QRS notching or slurring (J wave) in multiple leads, especially the inferior and/or left precordial leads. Although this finding has been considered to be a benign ECG manifestation, Haïssaguerre et al repor

• br Discussion In this pilot study we

  2019-06-05

  

  Discussion In this pilot study, we report that sequential treatment of low dose clofarabine and lenalidomide is safe and feasible for elderly patients with high risk MDS and AML. Only one subject developed dose limiting toxicity (liver dysfunction) from lenalidomide consolidation therapy. Pre-tre

• Adipose tissue represents an alternative

  2019-06-05

  

  Adipose tissue represents an alternative source of MSC-like cells, avoiding the problems of pain, morbidity and low cell number associated with bone marrow harvest [17]. In plastic and reconstructive surgery, adipose tissue-derived stromal dna methyltransferase (ADSCs) may be used to increase in si

• Illicit financial flight is the unrecorded movement of

  2019-06-01

  

  Illicit financial flight is the unrecorded movement of capital out of a country in contravention of the regulations of that country. The main mechanism used to undertake this is multinational companies shifting their tax liabilities to sister companies located in low tax jurisdictions, also known as

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