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The studies from several laboratories
2019-06-21
The studies from several laboratories suggest that miR-34 family members are the direct targets of TP53, and their upregulation can induce cancer cell apoptosis and cell-cycle arrest. It has been found that miR-34 is associated with prognosis, carcinogenesis, and survival of various cancers, includi
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br Discussion The major finding in this
2019-06-21
Discussion The major finding in this case is that implantation of an active-fixation atrial pacing lead in the right atrial appendage caused right coronary artery perforation, resulting in life-threatening tamponade. Myocardial perforation with or without cardiac tamponade has been reported as a
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dna methyltransferase br Conclusions Wavelet algorithm is an
2019-06-21
Conclusions Wavelet algorithm is an effective tool for the discrimination of tachycardia. However, it is affected by myopotential interference, which can lead to inappropriate detections. Thus, we should keep this drawback in mind when results reveal a Can-RV coil EGM amplitude of less than 5mV.
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El fuego como paradoja de la persistencia y del cambio
2019-06-21
El fuego como paradoja de la persistencia y del cambio Penetrar la cosmología poética de José Emilio Pacheco supone enfrentarse N-Acetylneuraminic acid la paradoja entre la persistencia de la materia y su transformación. El signo global que fecunda la dinámica expresiva de la escritura en este caso
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In addition we demonstrated that the combination of PCBP siR
2019-06-21
In addition, we demonstrated that the combination of PCBP2 siRNA and LY2109761 had a potent silencing effect on collagen expression (Fig. 8). Both HSC-T6 2\'-O-Methyl-ATP and primary HSCs were used to evaluate the combinational treatment. LY2109761, a TGFβ receptor type I/II kinase inhibitor, has b
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The WHO Safer Primary Care report has grappled head
2019-06-21
The WHO Safer Primary Care report has grappled head-on with the challenges associated with many variations in the scope, nature, and provision of primary care in different countries; insufficient data from low-income and middle-income country settings to inform priorities for care; the need to devel
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We discussed in our report
2019-06-21
We discussed in our report the potential to improve vaccine acceptance and increase demand for OPV by engaging people within communities to deliver health education. Our analysis focused on all reported sources of health education within a community—ie, not only traditional leaders but also the loca
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The greater relative importance of indirect causes could be
2019-06-21
The greater relative importance of indirect causes could be a result of successful addressing of direct complications of pregnancy and childbirth, and of a change in risk factors and disease patterns. Indirect causes of death include the effects of pre-existing disorders, such as HIV infection, ment
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Sultan et al retrospectively searched the surveillance epide
2019-06-20
Sultan et al retrospectively searched the surveillance, epidemiology, and end results (SEER) database for patients who were diagnosed with NPC from 1988 to 2006. They compared the clinical features and outcomes of 129 children and adolescents (n and young adults compared with older adults with nasop
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br Case A year old Caucasian male with a
2019-06-20
Case 4 A 59 year old Caucasian male with a history of chronic renal insufficiency was transferred to our intensive care unit from an outside hospital, intubated secondary to respiratory failure and severe mucositis. He arrived on multiple broad spectrum buy EHNA hydrochloride for treatment of he
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The PAX gene encodes a transcriptional factor which is speci
2019-06-20
The PAX5 gene encodes a transcriptional factor, which is specifically expressed at the early stages of B-cell differentiation and it is required for B-cell development. Its dysregulation is involved in the leukemogenesis of B-ALL. The PAX5 gene rearrangements account for approximately 2.5% of pediat
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br It is encouraging to read in the Article by
2019-06-20
It is encouraging to read in the Article by Mercy Kanyuka and colleagues (March, 2016) about Malawi\'s success in reducing child mortality, but I fear the authors might have missed one of the key factors contributing towards this great achievement. Specifically, that Malawi is unique in sub-Sahara
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We used MRI images taken to weeks after
2019-06-20
We used MRI images taken 1 to 8 weeks after a crisis to explore basal ganglion involvement and found restricted estrogen receptors at the basal ganglion. This finding suggests that cytotoxic damage to the basal ganglion persists post-crisis. When MRI images were obtained much longer after crisis, r
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Although the CHADS score is useful
2019-06-20
Although the CHADS2 score is useful for evaluating the risk of stroke in NVAF patients, about half of all NVAF patients have a score of 0 or 1 [7]. There are no clear guidelines on whether warfarin should be administered or not, to these patients because the risk of annual incidence of stroke is so
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br Discussion Primary lymphoma of
2019-06-20
Discussion Primary lymphoma of bone is a rare disease, first described by Oberling in 1928 and he labeled it as reticulum cell sarcoma of bone because of the presence of characteristic reticulin fibers within the lesion [5]. This work was followed by Parker and Jackson and later by Ivin and Bosto
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